barrier-to-autointegration factor

'barrier-to-autointegration factor' can also refer to...


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A small conserved protein (BAF, breakpoint cluster region protein 1, 89 aa) that has an important role in nuclear assembly, chromatin organization, gene expression, and gonad development. It is exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA.

Subjects: Medicine and Health.

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