base-pair substitution

'base-pair substitution' can also refer to...

base-pair substitution

base-pair substitution

Metal ion binding of substituted pyrimidine base pairs in DNA duplexes

Propynyl groups in duplex DNA: stability of base pairs incorporating 7‐substituted 8‐aza‐7‐deazapurines or 5‐substituted pyrimidines

Kinetics of formation of hypoxanthine containing base pairs by HIV-RT: RNA template effects on the base substitution frequencies

Ab initio molecular orbital evaluation of the hydrogen bond energy of base pairs formed between substituted 1-methylcytosine derivatives and 9-methylguanine

Evaluation of the hydrogen bond energy of base pairs formed between substituted 9-methyladenine derivatives and 1-methyluracil by use of molecular orbital theory

Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution

Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA

Molecular dynamics simulations and coupled nucleotide substitution experiments indicate the nature of A·A base pairing and a putative structure of the coralyne-induced homo-adenine duplex

The NMR studies of substituent effects on the N-H···N hydrogen bond in duplex DNA using 2′-deoxynebularine and 15N labeled 5-substituted-2′-deoxyuridine base pairs

Porcine Vitronectin, the Most Compact Form of Single-Chain Vitronectin: The Smallest Molecular Mass among Vitronectins Was Ascribed to Deletion and Substitution of Base Pairs, and Proteolytic Trimming of the Peptide


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A type of lesion in a DNA molecule that results in a mutation. There are two subtypes. In the case of transitions, one purine is substituted by the other or one pyrimidine by the other, and so the purine-pyrimidine axis is preserved. In the case of transversions, a purine is substituted by a pyrimidine or vice versa, and the purine-pyrimidine axis is reversed. See Chronology, 1959, Freese.

Subjects: Genetics and Genomics.

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