base-pair substitution

'base-pair substitution' can also refer to...

base-pair substitution

base-pair substitution

Metal ion binding of substituted pyrimidine base pairs in DNA duplexes

Propynyl groups in duplex DNA: stability of base pairs incorporating 7‐substituted 8‐aza‐7‐deazapurines or 5‐substituted pyrimidines

Kinetics of formation of hypoxanthine containing base pairs by HIV-RT: RNA template effects on the base substitution frequencies

Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution

Ab initio molecular orbital evaluation of the hydrogen bond energy of base pairs formed between substituted 1-methylcytosine derivatives and 9-methylguanine

Evaluation of the hydrogen bond energy of base pairs formed between substituted 9-methyladenine derivatives and 1-methyluracil by use of molecular orbital theory

Porcine Vitronectin, the Most Compact Form of Single-Chain Vitronectin: The Smallest Molecular Mass among Vitronectins Was Ascribed to Deletion and Substitution of Base Pairs, and Proteolytic Trimming of the Peptide

Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA

Molecular dynamics simulations and coupled nucleotide substitution experiments indicate the nature of A·A base pairing and a putative structure of the coralyne-induced homo-adenine duplex

The NMR studies of substituent effects on the N-H···N hydrogen bond in duplex DNA using 2′-deoxynebularine and 15N labeled 5-substituted-2′-deoxyuridine base pairs


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A type of lesion in a DNA molecule that results in a mutation. There are two subtypes. In the case of transitions, one purine is substituted by the other or one pyrimidine by the other, and so the purine-pyrimidine axis is preserved. In the case of transversions, a purine is substituted by a pyrimidine or vice versa, and the purine-pyrimidine axis is reversed. See Chronology, 1959, Freese.

Subjects: Genetics and Genomics.

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