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The oxidized form of tetrahydrobiopterin, a coenzyme essential for the conversion of phenylalanine to tyrosine, tyrosine to l-dopa, and tryptophan to 5-hydroxytryptophan. It is also an essential cofactor for nitric oxide synthase (NOS). Defects in biopterin synthesis can lead to hyperphenylalaninemia, a disorder similar to phenylketonuria.

Subjects: Medicine and Health — Chemistry.

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