Overview

BK channels


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Calcium-activated potassium channels (Maxi-K or slo1 channels) that allow calcium and potassium ions through cell membranes. They are activated (opened) by changes in membrane potential and/or intracellular Ca2+. The pore-forming α subunit is the product of the KCNMA1 gene, and there are four types of modulatory β subunits (encoded by KCNMB1, KCNMB2, KCNMB3, or KCNMB4); the pore has eight subunits with the stoichiometry α4β4.

Subjects: Medicine and Health.


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