BTB/POZ domain

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A structurally well-conserved domain (bric-a-brac tramtrack broad/poxvirus and zinc finger complex, POZ/BTB domain, BTB domain, ~120 aa) involved in protein–protein interactions and found in several zinc finger and poxvirus proteins. Mediates homo- or heterodimer formation of complexes involved in transcriptional regulation, cytoskeleton dynamics, ion channel assembly and gating, and targeting for ubiquitination.

http://pawsonlab.mshri.on.ca/index.php?option=com_content&task=view&Itemid=64&id=197 Structural details of the BTB/POZ domain.

Subjects: Medicine and Health.

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