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CADASIL


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A disorder (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) characterized by relapsing strokes with neuropsychiatric symptoms that affects relatively young adults of both sexes. Caused by a mutation in notch-3 which has various effects but particularly on vascular smooth muscle, hence perhaps the arteriopathy.

Subjects: Medicine and Health.


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