Overview

CAD


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1. A multifunctional protein (2225 aa) with the enzymatic activities required for the first three steps of the de novo pyrimidine synthesis pathway: glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5), aspartate carbamoyltransferase (EC 2.1.3.2), and dihydro-orotase (EC 3.5.2.3). It is allosterically regulated and loses feedback inhibition when phosphorylated.

2. See DNA fragmentation factor.

Subjects: Chemistry — Medicine and Health.


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