calcineurin inhibitors

'calcineurin inhibitors' can also refer to...

calcineurin inhibitors

calcineurin inhibitors

topical calcineurin inhibitors

topical calcineurin inhibitors

How calcineurin inhibitors cause hypertension

Calcineurin inhibitor toxicity in a renal transplant recipient

Calcineurin inhibitors in HLA-identical living related donor kidney transplantation

Pharmacodynamic monitoring of calcineurin inhibitor therapy: Is there a clinical benefit?

Corticosteroid and calcineurin inhibitor sparing regimens in kidney transplantation

Calcineurin‐inhibitors in renal transplantation. Too precious to be abandoned


Calcineurin inhibitors suppress the high-temperature stress sensitivity of the yeast ubiquitin ligase Rsp5 mutant: a new method of screening for calcineurin inhibitors

The calcineurin inhibitor RCAN1 is involved in cultured macrophage and in vivo immune response

FK506, a Calcineurin Inhibitor, Prevents Cadmium-Induced Testicular Toxicity in Mice

Genomic-Derived Markers for Early Detection of Calcineurin Inhibitor Immunosuppressant–Mediated Nephrotoxicity

Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: changes in glomerular haemodynamics and proteinuria

Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: benefits and risks

Cytochrome P450 3A5 expression in the kidneys of patients with calcineurin inhibitor nephrotoxicity

Stable graft function after reduction of calcineurin inhibitor dosage in paediatric kidney transplant patients


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Drugs that act by inhibiting the calcium-dependent protein phosphatase calcineurin, an enzyme that initiates a sequence of events that bring about activation of T lymphocytes. The group includes ciclosporin and tacrolimus, which are major maintenance immunosuppressants used in transplantation. Topical calcineurin inhibitors (e.g. tacrolimus, pimecrolimus [Elidel]) are used in the treatment of eczema when topical steroids have failed or are contraindicated. Stinging is a common transient side-effect, and reactivation of infections may occur.

Subjects: Medicine and Health.

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