Overview

calcineurin inhibitors


'calcineurin inhibitors' can also refer to...

calcineurin inhibitors

calcineurin inhibitors

topical calcineurin inhibitors

topical calcineurin inhibitors

How calcineurin inhibitors cause hypertension

Calcineurin inhibitor toxicity in a renal transplant recipient

SP684A CALCINEURIN INHIBITOR WITH AN IMPROVED SIDE EFFECT PROFILE?

Calcineurin inhibitors in HLA-identical living related donor kidney transplantation

Pharmacodynamic monitoring of calcineurin inhibitor therapy: Is there a clinical benefit?

Corticosteroid and calcineurin inhibitor sparing regimens in kidney transplantation

Calcineurin‐inhibitors in renal transplantation. Too precious to be abandoned

Calcineurin inhibitors suppress the high-temperature stress sensitivity of the yeast ubiquitin ligase Rsp5 mutant: a new method of screening for calcineurin inhibitors

The calcineurin inhibitor gossypol impairs growth, cell signalling and development in Dictyostelium discoideum

The calcineurin inhibitor RCAN1 is involved in cultured macrophage and in vivo immune response

Pain syndrome with stress fractures in transplanted patients treated with calcineurin inhibitors

In vitro interaction of posaconazole with calcineurin inhibitors and sirolimus against zygomycetes

Calcineurin inhibitor-induced pain syndrome after kidney transplantation—a rare but disabling condition

Combination of caspofungin with inhibitors of the calcineurin pathway attenuates growth in vitro in Aspergillus species

DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

 

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Drugs that act by inhibiting the calcium-dependent protein phosphatase calcineurin, an enzyme that initiates a sequence of events that bring about activation of T lymphocytes. The group includes ciclosporin and tacrolimus, which are major maintenance immunosuppressants used in transplantation. Topical calcineurin inhibitors (e.g. tacrolimus, pimecrolimus [Elidel]) are used in the treatment of eczema when topical steroids have failed or are contraindicated. Stinging is a common transient side-effect, and reactivation of infections may occur.

Subjects: Medicine and Health.


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