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'camptothecin' can also refer to...


Separation of 9-Methoxycamptothecin and Camptothecin from Nothapodytes foetida by Semipreparative HPLC

Self-defensive nano-assemblies from camptothecin-based antitumor drugs

Reduced apoptotic response to camptothecin in CHO cells deficient in XRCC3

Characterization of the antitumor-promoting activity of camptothecin in SENCAR mouse skin

The anti-cancer drug camptothecin inhibits elongation but stimulates initiation of RNA polymerase II transcription

Spatial organization of topoisomerase I‐mediated DNA cleavage induced by camptothecin–oligonucleotide conjugates

In vivo sequencing of camptothecin-induced topoisomerase I cleavage sites in human colon carcinoma cells

Comparison of camptothecin derivatives presently in clinical trials: genotoxic potency and mitotic recombination

The involvement of chromatin condensation in camptothecin-induced chromosome breaks in G0 human lymphocytes

Variations in the secondary metabolite camptothecin in relation to tissue age and season in Camptotheca acuminata

Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I

Belotecan, new camptothecin analogue, is active in patients with small-cell lung cancer: results of a multicenter early phase II study

A phase I clinical and pharmacokinetic study of the camptothecin glycoconjugate, BAY 38-3441, as a daily infusion in patients with advanced solid tumors

Concerted escalation of dose and dosing duration in a phase I study of the oral camptothecin gimatecan (ST1481) in patients with advanced solid tumors

The Utility of Camptothecin as a Synergist of Bacillus thuringiensis var. kurstaki and Nucleopolyhedroviruses Against Trichoplusia ni and Spodoptera exigua

Prospecting for Camptothecines from Nothapodytes nimmoniana in the Western Ghats, South India: Identification of High-Yielding Sources of Camptothecin and New Families of Camptothecines

Camptothecin Biosynthetic Genes in Hairy Roots of Ophiorrhiza pumila: Cloning, Characterization and Differential Expression in Tissues and by Stress Compounds

Hypersensitivity to camptothecin in MSH2 deficient cells is correlated with a role for MSH2 protein in recombinational repair


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A cytotoxic alkaloid that inhibits DNA topoisomerase I, originally isolated from Camptotheca acuminata (cancer tree, tree of life). Various derivatives such as CPT-11 (Irinotecan) are used as antitumour drugs.

Subjects: Medicine and Health.

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