cartilage oligomeric matrix protein

Quick Reference

One of the thrombospondin family of proteins (757 aa), present at high levels in the matrix surrounding chondrocytes. There are five identical glycoprotein subunits, each with EGF-like and calcium-binding domains. Mutations cause pseudoachondroplasia or a milder allelic disorder, epiphyseal dysplasia.

Subjects: Chemistry.

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