casein phosphopeptide-amorphous calcium phosphate

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A casein derived peptide, with added calcium and phosphate. It provides a phosphate and calcium reservoir when included within dental plaque and on the surface of the tooth. Amorphous calcium phosphate (ACP) is made by combining soluble salts of calcium and phosphorous. Calcium and phosphate ions are released when the pH drops during an acid attack, to maintain supersaturated surroundings with respect to hydroxyapatite and as a result reducing demineralization and increasing remineralization. CCP-ACP has a buffering effect on the acids produced in dental plaque and therefore has applications in the control of caries, especially uncontrolled root caries. It can be delivered to the tooth surface in a variety of ways such as chewing gum, lozenges, topical crème, mouthrinses, toothpaste, and as an additive in glass ionomer cement restorative material. Trade names: CPP-ACP™, Recaldent™, GC Tooth Mousse.

Subjects: Dentistry.

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