catabolite activating protein

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A constitutively produced, dimeric, positive regulator protein in bacteria that, when bound to a promoter region and cAMP, facilitates transcription by RNA polymerase of certain catabolite-sensitive adjacent genes in inducible and glucose-sensitive operons (such as the lac operon of E. coli). Also known as cyclic AMP receptor protein (CRP) or catabolite gene activator (CGA) protein.

Subjects: Chemistry — Genetics and Genomics.

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