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CD4, CD8 receptors


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Proteins on the surface of T lymphocytes (q.v.) that determine their responses to antigens. Lymphocytes with the CD8 proteins on their surfaces function as killer T lymphocytes (Tk cells). Lymphocytes with the CD4 proteins on their surfaces function as helper T lymphocytes (Th cells). These secrete interleukins (q.v.), which activate Tk cells and B lymphocytes. See immunoglobulin domain superfamily.

Subjects: Genetics and Genomics.


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