Overview

CD45


'CD45' can also refer to...

CD45

Altered CD45 isoform expression affects lymphocyte function in CD45 Tg mice

CD45 regulates apoptosis in peripheral T lymphocytes

CD45 up-regulation during lymphocyte maturation

Physical and functional association of CD45 and CD3-TCR complex on CD1+ human thymocytes. Evidence that the engagement of CD45 molecules can prevent CD1+ thymocytes from apoptosis

CD4+ T cell hyper-responsiveness in CD45 transgenic mice is independent of isoform

Evidence for down-regulation of highly expressed TCR by CD4 and CD45 on non-selected CD4+CD8+thymocytes

Domain organization of the extracellular region of CD45

Severe Combined Immunodeficiency Due to Mutations in the CD45 Gene

Evidence that human CD8+CD45RA+CD27– cells are induced by antigen and evolve through extensive rounds of division

CD45 can act as a negative regulator for the transition from early to late CD4+CD8+ thymocytes

Could the lower frequency of CD8+CD18+CD45RO+ lymphocytes be biomarkers of human VL?

CD4+CD45RA+T cells from adults respond to recall antigens after CD28 ligation

CD45RA(bright)/CD11a(bright) CD8+ T cells: effector T cells.

Targeting CD45RB alters T cell migration and delays viral clearance

T-cell activation results in microheterogeneous changes in glycosylation of CD45

CD45-mediated signals can trigger shedding of lymphocyte L-selectin.

Anti‐CD45RB antibody deters xenograft rejection by modulating T cell priming and homing

Engagement of CD45 during in vitro priming enhances antigen-specific Th cell frequencies

 

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Quick Reference

A CD marker present on T lymphocytes. It is the receptor for the membrane protein CD22, present in B lymphocytes. Binding of the ligand activates the protein tyrosine kinases Fyn and Lck.

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Subjects: Chemistry.


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