Overview

CD45


'CD45' can also refer to...

CD45

Altered CD45 isoform expression affects lymphocyte function in CD45 Tg mice

CD45 regulates apoptosis in peripheral T lymphocytes

CD45 up-regulation during lymphocyte maturation

Physical and functional association of CD45 and CD3-TCR complex on CD1+ human thymocytes. Evidence that the engagement of CD45 molecules can prevent CD1+ thymocytes from apoptosis

Evidence for down-regulation of highly expressed TCR by CD4 and CD45 on non-selected CD4+CD8+thymocytes

CD4+ T cell hyper-responsiveness in CD45 transgenic mice is independent of isoform

Domain organization of the extracellular region of CD45

Severe Combined Immunodeficiency Due to Mutations in the CD45 Gene

Evidence that human CD8+CD45RA+CD27– cells are induced by antigen and evolve through extensive rounds of division

CD45 can act as a negative regulator for the transition from early to late CD4+CD8+ thymocytes

Could the lower frequency of CD8+CD18+CD45RO+ lymphocytes be biomarkers of human VL?

CD4+CD45RA+T cells from adults respond to recall antigens after CD28 ligation

CD45RA(bright)/CD11a(bright) CD8+ T cells: effector T cells.

Targeting CD45RB alters T cell migration and delays viral clearance

T-cell activation results in microheterogeneous changes in glycosylation of CD45

CD45-mediated signals can trigger shedding of lymphocyte L-selectin.

Anti‐CD45RB antibody deters xenograft rejection by modulating T cell priming and homing

Engagement of CD45 during in vitro priming enhances antigen-specific Th cell frequencies

 

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Quick Reference

A CD marker present on T lymphocytes. It is the receptor for the membrane protein CD22, present in B lymphocytes. Binding of the ligand activates the protein tyrosine kinases Fyn and Lck.

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Subjects: Chemistry.


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