Overview

CD2-associated protein


Related Overviews

 

'CD2-associated protein' can also refer to...

 

More Like This

Show all results sharing this subject:

  • Medicine and Health

GO

Show Summary Details

Quick Reference

A multifunctional adaptor-type molecule (CAS ligand with multiple SH3 domains, 639 aa), which is localized in the cytoplasm, membrane ruffles, and leading edges of cells. It colocalizes with F-actin and p130cas and is involved in regulating the distribution of CD2, the T-cell surface marker involved in adhesion to antigen-presenting cells (the CD2–LFA3 interaction). Mutations are associated with focal segmental glomerulosclerosis 3.

Subjects: Medicine and Health.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.