cell fractionation

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The separation of the various components of cells after homogenization of a tissue and differential centrifugation. Four fractions are generally obtained: (1) the nuclear fraction, (2) the mitochondrial fraction, (3) the microsomal fraction, and (4) the soluble fraction or cytosol. See Chronology, 1946, Claude.

Subjects: Medicine and Health — Genetics and Genomics.

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