A fluid obtained by rupturing cells and removing the particulate material, membranes, and remaining intact cells. The extract contains most of the soluble molecules of the cell. The preparation of cell-free extracts in which proteins and nucleic acids are synthesized represent milestones in biochemical research. See Chronology, 1955, Hoagland; 1961, Nirenberg and Matthaei; 1973, Roberts and Preston.
Subjects: Genetics and Genomics — Chemistry.