Overview

centrins


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A family of EF-hand calcium-binding phosphoproteins involved in the structure and function of the microtubule organizing centre. There are three isoforms: centrin-1 (caltractin isoform 2, 172 aa), centrin-2 (caltractin isoform-1, 172 aa), which is essential for centriole duplication and correct spindle formation and interacts with calmodulin and centriolin, and centrin-3 (167 aa).

Subjects: Medicine and Health.


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