centromeric coupling

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The forming of paired centromeres early in diplonema. At first a protein encoded by Zip 1 (q.v.) holds the centromeres of homologous and nonhomologous chromosomes together indiscriminately. But as time passes, the number of homologous pairs increases, even though the total number of coupled centromeres remains the same. This observation suggests that the Zip 1 protein holds the centromeres together while chromosome homology is assessed. Then when correct pairing is achieved, synaptonemal complexes are constructed between the homologs. See Gowen crossover suppressor.

Subjects: Genetics and Genomics.

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