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cernunnos


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A DNA repair protein (nonhomologous end-joining factor 1, 299 aa) that interacts with the XRCC4/DNA-ligase IV complex in repairing double-strand breaks in DNA and V(D)J recombination that generates diversity in the immune system. Defects in cernunnos lead to a severe immunodeficiency condition associated with microcephaly and other developmental defects. See nonhomologous end-joining.

Subjects: Medicine and Health.


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