Overview

checkpoint kinase


'checkpoint kinase' can also refer to...

checkpoint kinase

Checkpoint kinase 1 negatively regulates somatic hypermutation

Protein kinase C controls activation of the DNA integrity checkpoint

Identification of XAF1 as a novel cell cycle regulator through modulating G2/M checkpoint and interaction with checkpoint kinase 1 in gastrointestinal cancer

Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA

Involvement of fission yeast Clr6-HDAC in regulation of the checkpoint kinase Cds1

A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration

Deoxycytidine kinase regulates the G2/M checkpoint through interaction with cyclin-dependent kinase 1 in response to DNA damage

Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model

P6.14Identification of selective inhibitors of the spindle assembly checkpoint kinase TTK (Mps1) for treatment of triple negative breast cancer

MB-22CHECKPOINT KINASE 1 EXPRESSION IS AN ADVERSE PROGNOSTIC MARKER AND THERAPEUTIC TARGET IN MYC-DRIVEN MEDULLOBLASTOMA

Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM

Polo-like kinase 1 enhances survival and mutagenesis after genotoxic stress in normal cells through cell cycle checkpoint bypass

Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases

117PDClinical relevance of DNA damage modulator checkpoint kinase 1 (CHK1) and cancerous inhibitor of protein phosphatase 2A (CIP2A) in human gliomas

 

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Quick Reference

A cell‐cycle checkpoint protein kinase that is activated in response to DNA damage. Its action prevents the cell from entering mitosis.

Subjects: Chemistry.


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