Overview

chromatin immunoprecipitation


'chromatin immunoprecipitation' can also refer to...

chromatin immunoprecipitation

chromatin immunoprecipitation

chromatin immunoprecipitation

Fast chromatin immunoprecipitation assay

Applications of chromatin immunoprecipitation-based epigenomic tools in nutritional studies

Analysis of transcription factor interactions in osteoblasts using competitive chromatin immunoprecipitation

Extensive chromatin fragmentation improves enrichment of protein binding sites in chromatin immunoprecipitation experiments

Probing flagellar promoter occupancy in wild-type and mutant Caulobacter crescentus by chromatin immunoprecipitation

μChIP—a rapid micro chromatin immunoprecipitation assay for small cell samples and biopsies

The use of biotin tagging in Saccharomyces cerevisiae improves the sensitivity of chromatin immunoprecipitation

Identifying estrogen receptor α target genes using integrated computational genomics and chromatin immunoprecipitation microarray

Optimization of experimental design parameters for high-throughput chromatin immunoprecipitation studies

Weighted enrichment method for prediction of transcription regulators from transcriptome and global chromatin immunoprecipitation data

Binding of lac repressor-GFP fusion protein to lac operator sites inserted in the tobacco chloroplast genome examined by chromatin immunoprecipitation

Nanobody®-based chromatin immunoprecipitation/micro-array analysis for genome-wide identification of transcription factor DNA binding sites

Combining chromatin immunoprecipitation and DNA footprinting: a novel method to analyze protein–DNA interactions in vivo

Identification of a direct Dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation

Microplate-based chromatin immunoprecipitation method, Matrix ChIP: a platform to study signaling of complex genomic events

RNAPol-ChIP: a novel application of chromatin immunoprecipitation to the analysis of real-time gene transcription

 

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A technique for identifying a specific DNA sequence in the genome (q.v.) to which a particular protein binds in vivo (q.v.). In this procedure, the protein in question is cross-linked to DNA with formaldehyde in vivo. The DNA is then extracted from cells and sheared into small fragments. Antibodies against the bound protein are then used to isolate the protein-DNA complex, the protein is released, and the polymerase chain reaction (PCR) (q.v.) is used to amplify the DNA sequence to which the protein was bound. The amplified DNA can then be identified by sequence analysis.

Subjects: Chemistry — Genetics and Genomics.


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