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'cis-activation' can also refer to...


HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop

Neural fate decisions mediated by trans-activation and cis-inhibition in Notch signaling

A versatile cis-blocking and trans-activation strategy for ribozyme characterization

A Transcription Factor γMYB1 Binds to the P1BS cis-Element and Activates PLA2-γ Expression with its Co-Activator γMYB2

cis-Activation of the Human Telomerase Gene (hTERT) by the Hepatitis B Virus Genome

CIS1 Interacts with the Y532 of the Prolactin Receptor and Suppresses Prolactin-Dependent STAT5 Activation

Mutational Analysis of Regulatory cis-acting Elements for the Transcriptional Activation of the dmsCBA Operon in Rhodobacter sphaeroides f. sp. denitrificans

Combined Effects of Multiple cis-Acting Elements in Elicitor-Mediated Activation of PSCHS1 Gene

ATRA activates and PDGF-BB represses the SM22α promoter through KLF4 binding to, or dissociating from, its cis-DNA elements

New invMED1 element cis-activates human multidrug-related MDR1 and MVP genes, involving the LRP130 protein

Identification of cis-acting elements in the SUC2 promoter of Saccharomyces cerevisiae required for activation of transcription

Differential Contributions of ATF6 and XBP1 to the Activation of Endoplasmic Reticulum Stress-Responsive cis-Acting Elements ERSE, UPRE and ERSE-II

Functional Analysis of the Putative cis-Elements Involved in Activation by Elicitor or UV and Deactivation by Suppressor in the Promoter of a Pea Gene for Phenylalanine Ammonia-lyase (PSPAL1)

cis-9,trans-11-Conjugated linoleic acid down-regulates phorbol ester-induced NF-κB activation and subsequent COX-2 expression in hairless mouse skin by targeting IκB kinase and PI3K-Akt

Cis elements for transporter associated with antigen-processing-2 transcription: two new promoters and an essential role of the IFN response factor binding element in IFN-γ-mediated activation of the transcription initiator


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Activation brought about by something on the same cell or on the same chromosome. There are examples of cis-activation of adhesion molecules through protein–protein contacts that occur in the plane of the membrane but do not occur if the two molecules are in different cells. Cis-activation of a gene is brought about by activators binding to upstream regions of the chromosome, whereas trans-activation would involve a diffusible product. Compare transactivation.

Subjects: Medicine and Health.

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