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complement factor H


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complement factor H

In Vivo Binding of Complement Regulator Factor H by Streptococcus pneumoniae

Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease

Familial relapsing haemolytic uraemic syndrome and complement factor H deficiency.

Complement factor H Y402H decreases cardiovascular disease risk in patients with familial hypercholesterolaemia

Interaction of clinical isolates of Streptococcus pneumoniae with human complement factor H

Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H

Complement regulator factor H as a serum biomarker of multiple sclerosis disease state

Association Between Complement Regulatory Protein Factor H and AM34 Antigen, Detected in Senile Plaques

Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes

Site-specific N-glycan characterization of human complement factor H

Complement Factor H and Simian Virus 40 bind the GM1 ganglioside in distinct conformations

MP124FAMILY DEFECTS IN FACTOR H/FHRS OF THE COMPLEMENT IN IGA NEPHROPATHY

Complement factor H gene associations with end-stage kidney disease in African Americans

Serum complement factor H is associated with clinical and pathological activities of patients with lupus nephritis

Complement factor H mutation associated with membranoproliferative glomerulonephritis with transformation to atypical haemolytic uraemic syndrome

Importance of Inhibition of Binding of Complement Factor H for Serum Bactericidal Antibody Responses to Meningococcal Factor H-binding Protein Vaccines

Complement factor H (Y402H) polymorphism and risk of coronary heart disease in US men and women

Host Polymorphisms in Interleukin 4, Complement Factor H, and C-Reactive Protein Associated with Nasal Carriage of Staphylococcus aureus and Occurrence of Boils

 

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A serum glycoprotein (CFH, β-1H globulin, 1231 aa) that regulates the alternate complement pathway by binding to C3b, accelerating the decay of the alternate pathway convertase C3bBb, and acting as a cofactor for complement factor I. Genetic variations in CFH are associated with basal laminar drusen and with age-related macular degeneration type 4. Deficiency of CFH allows uncontrolled activation of the alternate pathway and is associated with a number of renal diseases, including membranoproliferative glomerulonephritis and atypical haemolytic uraemic syndrome. There is also increased susceptibility to meningococcal infections.

Subjects: Medicine and Health.


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