Overview

conotoxin


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A group of small peptide toxins from cone shells Conus spp. The α-conotoxins are competitive inhibitors of nicotinic acetylcholine receptors, the μ-conotoxins bind voltage-gated sodium channels in muscle, causing paralysis and the ω-conotoxins inhibit voltage-sensitive calcium channels and block synaptic transmission. See conantokins.

Subjects: Chemistry — Medicine and Health.


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