A class of genetic elements that renders target genes unstably hypermutable, as in the Dissociation-Activator system of corn (q.v.). They include receptors and regulators. The receptor element is a mobile genetic element that, when inserted into the target gene, causes it to become inactivated. The regulator gene maintains the mutational instability of the target gene, presumably by its capacity to release the receptor element from the target gene and thus return that locus to its normal function. See transposable elements.
Subjects: Genetics and Genomics.