coupling, repulsion configurations

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When both nonallelic mutants are present on one homolog and the other homologous chromosome carries the plus alleles (a b/++), the genes are said to be in the coupling configuration. The repulsion configuration refers to a situation in which each homolog contains a mutant and a wild-type gene (a+/+ b). See cis-trans configurations.

Subjects: Genetics and Genomics.

Reference entries