Overview

COUP-TFs


'COUP-TFs' can also refer to...

 

More Like This

Show all results sharing this subject:

  • Medicine and Health

GO

Show Summary Details

Quick Reference

Transcription factors (chick ovalbumin upstream promoter-transcription factors) of the steroid/thyroid hormone receptor family; but orphan receptors, since the ligands are unidentified. COUP-TFs play a role in glial cell development and central nervous system myelination. COUP-TF2 (414 aa) regulates the transcription of the apolipoprotein A-I gene. See ARP-1. COUP-TF-interacting protein 1 (B-cell lymphoma/leukaemia 11A, 835 aa) functions as a myeloid and B-cell proto-oncogene; chromosomal aberrations involving the gene may be a cause of lymphoid malignancies. COUP-TF-interacting protein-2 (894 aa) is a tumour-suppressor protein involved in T-cell lymphomas.

Subjects: Medicine and Health.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.