Overview

CTCF


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'CTCF' can also refer to...

CTCF

CTCF

CTCF protein

CTCF protein

The vertebrate protein CTCF functions as an insulator in Saccharomyces cerevisiae

Transcriptional repression by the insulator protein CTCF involves histone deacetylases

Molecular Weight Abnormalities of the CTCF Transcription Factor: CTCF Migrates Aberrantly in SDS-PAGE and the Size of the Expressed Protein is Affected by the UTRs and Sequences Within the Coding Region of the CTCF Gene

CTCF depletion alters chromatin structure and transcription of myeloid-specific factors

CTCFBSDB 2.0: a database for CTCF-binding sites and genome organization

Identification of CTCF as a master regulator of the clustered protocadherin genes

CTCFBSDB: a CTCF-binding site database for characterization of vertebrate genomic insulators

Retrovirus silencer blocking by the cHS4 insulator is CTCF independent

CTCF binds the proximal exonic region of hTERT and inhibits its transcription

Tissue specific CTCF occupancy and boundary function at the human growth hormone locus

The CSB chromatin remodeler and CTCF architectural protein cooperate in response to oxidative stress

A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiation

Defining the multivalent functions of CTCF from chromatin state and three-dimensional chromatin interactions

Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors

Selective interactions of boundaries with upstream region of Abd-B promoter in Drosophila bithorax complex and role of dCTCF in this process

 

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A transcriptional repressor (CCCTC-binding factor, 727 aa) that binds to promoters of c-myc, polo-like kinase, and PIM1 genes but is a transcriptional activator of the gene for amyloid precursor protein. May act as a tumour suppressor and mutations in the gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumours.

Subjects: Medicine and Health — Genetics and Genomics.


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