cyclic GMP

Show Summary Details

Quick Reference

Cyclic guanosine monophosphate, a compound that is analogous to cyclic AMP and that keeps sodium channels open in the outer membranes of rods and cones in the retina when its ring structure is intact, but is inactivated by transducin if stimulated by light, closing the sodium channels and triggering action potentials. It also relaxes the smooth muscles in the walls of arteries in the penis, causing the arteries to dilate and tending to constrict veins, its secretion increasing in response to sexual excitement and affecting the corpora cavernosa and the corpus spongiosum of the penis or clitoris, facilitating the inflow and reducing the outflow of blood into the erectile tissue. See also phosphodiesterase type 5, Viagra. cGMP abbrev.

Subjects: Psychology.

Reference entries

See all related reference entries in Oxford Index »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.