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cypin


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An alternatively spliced form of guanine deaminase (cytosolic PSD-95 interactor) that in neurons promotes an increase in dendrite numbers, an activity dependent on enzyme activity. It interacts with PSD-95 (See postsynaptic protein), and binds tubulin via its CRMP homology domain to promote microtubule assembly, an interaction blocked by snapin.

Subjects: Medicine and Health.


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