density enhanced phosphatase-1

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A transmembrane protein (Dep-1, CD148, protein-tyrosine phosphatase -η, HPTPε, EC, 1337 aa) with a single cytoplasmic tyrosine phosphatase domain. Dep-1 negatively regulates growth factor receptor signalling, may act as a tumour suppressor and may have a role in density dependent inhibition of growth.

Subjects: Medicine and Health.

Reference entries