An inflammatory condition of the oral mucosa associated with the wearing of dentures and the presence of Candida species. It is characterized by severe erythema and oedema of the denture-bearing area of the oral mucosa, occurring most frequently on the palate beneath a complete upper denture. Fungal infection may be evident in the form of asymptomatic white surface colonies. Risk factors associated with the condition are age-related chronic disease and drug therapy. Treatment is by improving denture hygiene, correcting any denture defects and the provision of antifungal therapy such as nystatin.