An increased synthesis of gene product accomplished by preventing the interaction of a repressor with the operator portion of the operon in question. In the case of inducible enzyme systems, the inducer derepresses the operon. A mutation of the regulatory gene that blocks synthesis of the repressor or a mutation of the operator gene that renders it insensitive to a normal repressor will also result in derepression. See regulator gene.
Subjects: Chemistry — Genetics and Genomics.