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desmoyokin


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A desmosomal plaque protein (5890 aa) from bovine muzzle keratinocytes that is thought to be dumbell-shaped and ~170 nm in length. The desmoyokin gene is identical to the human AHNAK gene, which is expressed ubiquitously but usually considered a nuclear protein, although also associated with membranes of enlargeosomes. Desmoyokin/Ahnak null mutant mice do not show any marked phenotype. The disparities continue to be puzzling.

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