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A muscle-specific type III intermediate filament protein (470 aa) that appears to mediate attachments between the terminal Z disc and the junctional membrane, as well as linking Z discs in series in each sarcomere. Colocalizes with synemin, paranemin, and plectin in the appropriate cell types. Defects lead to various forms of myopathy.

Subjects: Medicine and Health — Science and Mathematics.

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