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Devoret test


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An old name for a carcinogenicity test that continues to be used under a variety of different names (Microscreen Assay, Inductest). The readout is the induction of prophage lambda in bacteria, detected as plaques which occurs if carcinogens cause DNA damage and activate the SOS repair system which turn induces the phage. The correlation between carcinogenicity and prophage induction is good and it is claimed to be more sensitive than the Ames test.

Subjects: Medicine and Health.


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