Overview

diacylglycerol


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(DAG)

Glycerol with long chain fatty acyl residues substituted on the 1 and 2 hydroxyl groups. DAG is an intermediate in the biosynthesis of phosphatidyl phospholipids. DAG released by phospholipase C activity from phosphatidylinositol polyphosphates, acts as a second messenger and activates protein kinase C by stabilizing its catalytically active complex with membrane-bound phosphatidylserine and calcium.

Subjects: Medicine and Health.


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