Overview

dickkopf


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A family of secreted proteins (220–350 aa) that are inhibitors of Wnt signalling. Originally identified in Xenopus but human homologues (DKK1–4) have subsequently been identified. There is a DKK3-related protein designated ‘soggy’, (Dickkopf-like-1, DKKL1, 242 aa).

Subjects: Medicine and Health.


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