Directed Protein Evolution

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'Directed Protein Evolution' can also refer to...

Directed Protein Evolution

Engineering aggregation-resistant proteins by directed evolution

Directed evolution of an extremely stable fluorescent protein

Optimizing the search algorithm for protein engineering by directed evolution

Directed evolution of mammalian anti-apoptosis proteins by somatic hypermutation

Improved drug-like properties of therapeutic proteins by directed evolution

Directed evolution of O 6-alkylguanine-DNA alkyltransferase for applications in protein labeling

Covalent DNA display as a novel tool for directed evolution of proteins in vitro

Directed evolution of estrogen receptor proteins with altered ligand-binding specificities

Directed evolution of the peroxidase activity of a de novo-designed protein

Linking the functions of unrelated proteins using a novel directed evolution domain insertion method

Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis

ECSTASY, an adjustable membrane-tethered/soluble protein expression system for the directed evolution of mammalian proteins

Development of a screening platform for directed evolution using the reef coral fluorescent protein ZsGreen as a solubility reporter

Functional tuning of a salvaged green fluorescent protein variant with a new sequence space by directed evolution

Directed evolution of a type I antifreeze protein expressed in Escherichia coli with sodium chloride as selective pressure and its effect on antifreeze tolerance

Directed evolution of chemotaxis inhibitory protein of Staphylococcus aureus generates biologically functional variants with reduced interaction with human antibodies

SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution

Chemical and biochemical strategies for the randomization of protein encoding DNA sequences: library construction methods for directed evolution


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In the late 1980s, scientists began to develop techniques to alter protein function that do not require extensive knowledge of either protein structure or chemistry. They took notice of the ...

Subjects: Evolutionary Biology.

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