The process of removing all pathogenic bacteria from the mouth within a short space of time to reduce the risk of re-infection of treated periodontitis-affected sites. It involves complete root surface debridement of all natural teeth present in the oral cavity, carried out within a 24-hour period, supplemented by systemic antibiotic therapy. It is usually carried out over one or two clinical sessions and may be indicated for aggressive periodontitis and multiple periodontal abscesses. The evidence for the additional benefit of antiseptic use is currently inconclusive.
Eberhard J., Jepsen S., Jervøe-Storm P.-M., Needleman I., Worthington H. V. Full-mouth disinfection for the treatment of adult chronic periodontitis. Cochrane Database of Systematic Reviews 2008, Issue 1. Art. No.: CD004622. DOI: 10.1002/14651858.CD004622.pub2Farman M., Joshi R. I. Full-mouth treatment versus quadrant root surface debridement in the treatment of chronic periodontitis: a systematic review. Br Dent J 2008;205:E18.
http://www.library.nhs.uk/oralhealth/ViewResource.aspx?resID=279135 The NHS National Library for Health: a Cochrane systematic review of full mouth disinfection.