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DNA fiber autoradiography


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Light microscopic autoradiography of tritiated thymidine-labeled DNA molecules attached to millipore filters. The technique was devised by Cairns (1963) for studying DNA replication in E. coli and later adapted by Huberman and Riggs (1968) for visualizing the multiple replicons of mammalian chromosomes.

Subjects: Genetics and Genomics.


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