Overview

dna mutations


Show Summary Details

Quick Reference

Mutations of E. coli that influence DNA replication. The dna A, dna B, and dna C mutations are defective in proteins that interact with replication origins. The dna E, dna X, and dna Z genes encode subunits of DNA polymerase III, and dna G encodes primase (q.v.). Mutation in dnaQ damages the proofreading (q.v.) ability of the epsilon subunit of DNA polymerase III and greatly increases the mutation rate. See DNA polymerase, mutator gene, repair synthesis, replisome.

Subjects: Genetics and Genomics.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.