Overview

DNAzyme


'DNAzyme' can also refer to...

DNAzyme

Conjugate DNAzymes

A novel replicating circular DNAzyme

A DNAzyme requiring two different metal ions at two distinct sites

DNAzyme-mediated catalysis with only guanosine and cytidine nucleotides

RNA cleaving ‘10‐23’ DNAzymes with enhanced stability and activity

In vitro selection of a DNAzyme with three modified nucleotides

DNAzymes and ribozymes carrying 2′-C-methyl nucleotides

Rational evolution of Cd2+-specific DNAzymes with phosphorothioate modified cleavage junction and Cd2+ sensing

A new heavy lanthanide-dependent DNAzyme displaying strong metal cooperativity and unrescuable phosphorothioate effect

Insight into G-quadruplex-hemin DNAzyme/RNAzyme: adjacent adenine as the intramolecular species for remarkable enhancement of enzymatic activity

HIV-1 RT-dependent DNAzyme expression inhibits HIV-1 replication without the emergence of escape viruses

Insights into how nucleotide supplements enhance the peroxidase-mimicking DNAzyme activity of the G-quadruplex/hemin system

A general approach for the use of oligonucleotide effectors to regulate the catalysis of RNA-cleaving ribozymes and DNAzymes

Optimisation of the 10–23 DNAzyme–substrate pairing interactions enhanced RNA cleavage activity at purine–cytosine target sites

Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc finger transcription factor EGR‐1

Sequence‐specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities

A genotype-to-phenotype map of in vitro selected RNA-cleaving DNAzymes: implications for accessing the target phenotype

Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity

 

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a synthetic DNA molecule with catalytic properties.

Subjects: Chemistry.


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