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A part or region of a molecule or structure that has particular physicochemical features or properties, e.g. hydrophobic, polar, globular, α-helical domains, DNA-binding domain, ATP-binding domain. A range of domains are recognized on the basis of their sequence and their presence can be a helpful indicators of the likely function or location of a molecule.

http://pawsonlab.mshri.on.ca/index.php?option=com_content&task=section&id=3&Itemid=64 Useful website with links to details of many domains.

http://www.ncbi.nlm.nih.gov/sites/entrez?db=cdd The NCBI's Conserved Domains database.

Subjects: Medicine and Health.

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