domoic acid

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domoic acid

Domoic Acid Impairment of Cardiac Energetics

Glutathione Levels Modulate Domoic Acid–Induced Apoptosis in Mouse Cerebellar Granule Cells

Brain Fos Induction Is a Sensitive Biomarker for the Lowest Observed Neuroexcitatory Effects of Domoic Acid

Low-Level Domoic Acid Protects Mouse Cerebellar Granule Neurons from Acute Neurotoxicity: Role of Glutathione

Gene Expression Profiles in Zebrafish Brain after Acute Exposure to Domoic Acid at Symptomatic and Asymptomatic Doses

Repeated Independent Exposures to Domoic Acid Do Not Enhance Symptomatic Toxicity in Outbred or Seizure-Sensitive Inbred Mice

Persistent Neurological Damage Associated With Spontaneous Recurrent Seizures and Atypical Aggressive Behavior of Domoic Acid Epileptic Disease

Small Interfering RNA–Mediated Knockdown of Protein Kinase C Zeta Attenuates Domoic Acid–Induced Cognitive Deficits in Mice

From the Cover: Selective Enhancement of Domoic Acid Toxicity in Primary Cultures of Cerebellar Granule Cells by Lowering Extracellular Na+ Concentration

Pseudo-nitzschia species composition varies concurrently with domoic acid concentrations during two different bloom events in the Southern California Bight

Domoic acid production and elemental composition of two Pseudo-nitzschia multiseries strains, from the NW and SW Atlantic Ocean, growing in phosphorus- or nitrogen-limited chemostat cultures

Sequential Involvement of Distinct Glutamate Receptors in Domoic Acid-Induced Neurotoxicity in Rat Mixed Cortical Cultures: Effect of Multiple Dose/Duration Paradigms, Chronological Age, and Repeated Exposure

Domoic Acid Induces a Long-Lasting Enhancement of CA1 Field Responses and Impairs Tetanus-Induced Long-term Potentiation in Rat Hippocampal Slices


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A tricarboxylic acid toxin originally isolated from the macroscopic red alga Chondria armata, known in Japan as domoi, that is used as an anthelmintic in a traditional herbal medicine. An agonist for the kainate subclass of ionotropic glutamate receptors of the central nervous system. Domoic acid is the cause of amnesic shellfish poisoning, the source of the toxin being the diatom Pseudo-nitzschia (previously Nitzschia) pungens forma multiseries.

Subjects: Medicine and Health.

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