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domoic acid


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A tricarboxylic acid toxin originally isolated from the macroscopic red alga Chondria armata, known in Japan as domoi, that is used as an anthelmintic in a traditional herbal medicine. An agonist for the kainate subclass of ionotropic glutamate receptors of the central nervous system. Domoic acid is the cause of amnesic shellfish poisoning, the source of the toxin being the diatom Pseudo-nitzschia (previously Nitzschia) pungens forma multiseries.

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