Genes that specify the dorsal or ventral patterning program of the embryonic cells in which they are expressed. In Drosophila, the gene decapentaplegic specifies dorsal development, whereas its mouse homolog, BMP4, specifies ventral development. In Drosophila, the gene short gastrulation specifies ventral development, whereas the homologous gene in the mouse, chordin, specifies the dorsal development pattern. See Saint Hilaire hypothesis.
Subjects: Genetics and Genomics.