ecotropic virus

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Generally, a virus that will only replicate in its original host species. Most commonly refers to murine retroviruses, others of which infect only heterologous species (xenotropic viruses); a third category (amphotropic viruses) infect cells of both original and heterologous species. The distinction is important when considering the risks of xenografting; pig endogenous retroviruses (PERVs) have been shown to infect human cells.

Subjects: Medicine and Health.

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