Hypohidrotic ectodermal dysplasia, a congenital disorder of teeth, hair, and eccrine sweat glands, is usually inherited as an X-linked recessive trait, although rarer autosomal dominant and autosomal recessive forms are known. See IκB. McGrath's syndrome (ectodermal dysplasia syndrome) is caused by mutations in the plakophilin-1 gene. See desmosome; ectodysplasin.
Subjects: Medicine and Health.