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emperipolesis


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A phenomenon in which lymphocytes appear to be phagocytosed by macrophages (histiocytes) in the lymph node. This may be an artefact, since leucocytes moving underneath spread cells often appear, erroneously, to be within the larger flattened cells. In the early literature lymphocytes and leucocytes were thought to enter the cytoplasm of endothelial cells in order to cross the wall of the postcapillary venule and this was termed emperipolesis; subsequent ultrastructural studies have shown that this does not happen and leucocytes move between the endothelial cells.

Subjects: Medicine and Health.


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